We analyzed the effects of geraniol on the systemic inflammatory profile of IBS patients at V2, consisting of blood IL-1β, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12, IL-17A, IFN-γ, TNF-α, MCP-1, MIP-1β, and CCL28. The gene discussed is CCL4; the disease is irritable bowel syndrome.