EGFR and obesity due to melanocortin 4 receptor deficiency: Figure 6D describes the molecular function of DEGs enrichment. The HFD + EA + BC2000 group activated autophagy compared with the HFD group. Next, interaction network analysis based on the pathway of KEGG revealed that the addition of EA + BC2000 significantly affected metabolic pathways related to obesity and immune response, such as autophagy, mitophagy, NOD-like receptor signaling pathway, mTOR signaling pathway, ErbB signaling pathway, insulin resistance, and other metabolic pathways (Figure 6E).