A recent study found that urolithin A intervened in type 2 diabetic mice and found that the pancreatic protective effect of urolithin A in diabetes was mediated by its regulation of autophagy and AKT/mTOR signaling pathways, specifically urolithin A, which increased the phosphorylation levels of p-AKT and p-mTOR [27]. The gene discussed is AKT1; the disease is type 2 diabetes mellitus.