In our previous study, we focused on the effect of Carica papaya (C. papaya) on insulin signaling targets such as IR and GLUT4 in skeletal muscle of type 2 diabetes, as well as in silico analysis of the bioactive compounds of C. papaya against IR and GLUT-4, its enhancement in glucose uptake, and decrease in insulin resistance. Here, SLC2A4 is linked to Insulin resistance.