ACE2 and COVID-19: After screening a natural and FDA-approved compound libraries using homogeneous time resolved fluorescence, Li et al. found that TS-984 (9-methoxycanthin-6-one) suppresses the spike:ACE2 interaction via pseudovirus neutralization assay on ACE2-overexpressing 293T cells, suggesting that it may have potential as an anti-COVID-19 drug [27].