In fact, it appears to be particularly effective in overweight and obese women with PCOS, in which it was highlighted that after KD there is a 12% reduction in total weight, a 54% reduction in insulin levels, a 36% reversal of the luteinizing hormone (LH)/follicle-stimulating hormone (FSH) ratio, and a 22% reduction in free testosterone. This evidence concerns the gene INS and polycystic ovary syndrome.