BDNF and myeloid sarcoma: Researchers believe that aerobic or endurance training increases anandamides in cerebrospinal fluid and induce anti-inflammatory effects in the central nervous system, increasing CB1R and CB2R expression in both blood and brain and spinal cord tissue in EAE and MS patients through improving the function of the GABAergic system, improving neurotrophins, and improving cannabinoid analogues and antagonists [20].