At the present time, there is no convincing evidence that demonstrates a role for vitamin supplementation or other natural supplements in the fight against COVID-19: some positive results against viral infections have been provided for Vitamin B, especially B9 and B12 [14], Vitamin C [15], Vitamin D [16] and other substances such as lactoferrin [17], but evidence on the potential effects in the prevention and management of viral infections from clinical studies is still fragmented for VA. The gene discussed is LTF; the disease is viral infectious disease.