Figure 8A–C, Figure 6F and Figure S3 show that sedentary rats in the 2K1C renovascular hypertension group had enhanced AT-1R positive cells (Figure 8A,B, p < 0.001) and protein expression (Figure 6F and Figure S3, p < 0.001), and mRNA expression (Figure 8C, p < 0.01) in comparison with the sedentary SHAM rats. This evidence concerns the gene AGTR1 and renovascular hypertension.