Considering the multiple nutritional and biochemical factors that affect the patient’s health status, and particularly the ongoing inflammation in IBD patients, we aimed to use the cluster analysis method to reveal important links between three groups of relevant parameters: (i) those related to nutritional status (such as BMI and albumin levels); (ii) SCFA profile; and (iii) proinflammatory and anti-inflammatory cytokines (IL-6, IL-10, IL-17, IL-22, and TNF-α). The gene discussed is IL6; the disease is irritable bowel syndrome.