CD8A and neoplasm: Recently, Cheng et al. demonstrated that metastasis in CT26 tumor-bearing mice was inhibited by 2′3′-cGAMP via modulating the EMT process, although the major focus was on the effects of 2′3′-cGAMP regulating CD8+ T cells and myeloid-derived suppressor cells (MDSCs) in the tumor microenvironment [37].