Studies with intravenous Ghrelin include testing its use to control alcohol craving and use [90], evaluating the effects of Ghrelin administration on dopamine signaling in humans [91], examining the effects of short-term Ghrelin administration to humans on metabolism [92], including assessing the effects of acute Ghrelin administration on insulin resistance as measured by the hyperinsulinemic euglycemic clamp, and evaluating the effects of Ghrelin on local and systemic lipolysis. Here, GHRL is linked to Insulin resistance.