However, an association has been shown between disease severity (estimated based on Hurley staging system) and koebnerisin serum levels in patients with hidradenitis suppurativa (50.8 ± 30.9 pg/mL, 151.5 ± 115.7 pg/mL, 317.1 ± 101.0 pg/mL in Hurley stage I, II and III, respectively). Here, S100A7A is linked to hidradenitis suppurativa.