FURIN and cancer: As an example, Wang et al. rationally developed a furin-responsive radiotracer Acetyl-Arg-Val-Arg-Arg-Cys(StBu)-Lys-(DOTA-68Ga)-CBT (CBT-68Ga; DOTA is the abbreviation of “1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid”) and coinjected it with its cold analogue CBT-Ga in furin-overexpressing MDA-MB-468 cancer cells, leading to the formation of 68Ga nanoparticles (CBT-68Ga-NPs) [75].