The anticancer effects were correlated with a molecular docking study in order to assess a potential interaction between the compounds and the human NADPH-quinone oxidoreductase (NQO1) protein site; it was noticed that the biological activity of triterpenes increased in cell lines with higher levels of the NQO1 protein, such as melanoma (C-32) and breast (MCF-7) and lung (A-549) cancer. This evidence concerns the gene NQO1 and cancer.