Additionally, the endogenous n-6/n-3 PUFA ratio in adipose tissue was significantly lower in Fat-1 Ctrl (4.56 ± 0.43) and Fat-1 HF mice (4.78 ± 0.51) than in WT Ctrl (17.22 ± 2.00) and WT HF mice (19.83 ± 1.93) whatever they fed a Ctrl or HF diet (Figure 4C). Here, FAT1 is linked to hydrops fetalis.