Analysis of vascular risk factors in TGA patients on admission, in regard to sex-specific differences, showed significant higher systolic blood pressure (SBP) figures in female patients (173.2 ± 23.4 mm Hg versus 165.8 ± 22.0 mm Hg; p = 0.007), increased serum cholesterol levels (221.6 ± 40.7 mg/dL versus 207.6 ± 45.5 mg/dL; p = 0.005) as well as augmented C-reactive protein (CRP) levels (2.8 ± 6.4 mg/L versus 1.7 ± 1.8 mg/L; p = 0.011). Here, CRP is linked to transposition of the great arteries.