While the predictive value of radiotherapy, infusion time, CRP, calcium, natrium, and GGT (AUC 0.61–0.69, Figure 3a–f) showed only limited accuracy, with an AUC of 0.78 (95% CI: 0.7–0.86), decreased hemoglobin level, and lower ALC (AUC 0.71 (95% CI: 0.6–0.82), and showed the highest predictive value for IIN in sarcoma patients (Figure 3g,h). The gene discussed is CRP; the disease is sarcoma.