These modifications could be related to EA regulation of endogenous glucose production and glucose metabolism [25,26,27,28,29,30,31,32,33,34,35,36,37,38]; however, other measurements such as glucagon, which is regulated by glucose and suppressed by hyperinsulinemia [36], could be useful to a wide pathophysiological comprehension. The gene discussed is GCG; the disease is hyperinsulinism.