Migraine patients without aura, on the other hand, have correlations that patients with aura do not: between PAI-1 and MCP-1, sICAM-1; between MMP-9 and sICAM-1, MCP-1; between TGF-α and PAI-1, MMP-9, and sICAM-1; between sICAM-1 and MMP-9, PAI-1, and MCP-1; as well as between sVCAM-1 and MCP-1;. This evidence concerns the gene CCL2 and migraine disorder.