A multivariable Cox model confirmed that NT-pro BNP was independently associated with in-hospital death, after adjustment for all relevant confounders both in patients with a history of ASCVD: hazard ratio (HR) 2.63, 95% confidence interval (CI) 1.65–4.18, per logarithmic unit, and in patients without a history of ASCVD (HR 1.66, 95% CI 1.10–2.53, per logarithmic unit), Table 3, Figure 2. Here, NPPB is linked to atherosclerosis.