Out of the 50 glioma samples analyzed, ABCB1 was found methylated (at a methylation level higher than 10%) in 52% of the samples (26/50 samples); a mild methylation of ABCB1 (methylation level equals 10%) was detected in 14.0% of the samples (7/50), while unmethylated ABCB1 was found in 34.0% of the samples (17/50). This evidence concerns the gene ABCB1 and central nervous system cancer.