In multivariate analysis, the RDW-SD was independently associated with pulmonary embolism (OR = 1.188, 95% CI 1.048 to 1.348, p = 0.007) after adjusting for albumin, alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase, and D-dimer. The gene discussed is ALB; the disease is pulmonary embolism.