By genotyping the 5′ and 3’ ends, the expression of TS from patients’ peripheral blood before the chemotherapy treatment and by analyzing TS, TP and DPD genes in RNA extracted from a paraffin-embedded tumor, a translational study aimed to evaluate the response to a capecitabine chemotherapy regimen and also to identify the treatment associated toxicities in squamous cell carcinoma of the cervix cases. Here, TYMP is linked to neoplasm.