Among the 84 miRNAs, 8 presented fold-change > 2 in subjects with periodontitis in comparison to controls; 6 of such genes were found significantly upregulated in subjects with periodontitis in comparison to controls in a subsequent RT-PCR assay: MIR9-1, MIR155, MIR203A, MIR147A, MIR182, MIR183 genes [36] (Table 8) (Supplement Materials, Table S5). This evidence concerns the gene MIR182 and periodontitis.