During the EMT process, tumor cells lose their expression of specific epithelial markers, including epithelial cadherin (E-cadherin), epithelial cell adhesion molecule (EpCAM), and cytokeratins (CKs), and acquire the expression of cytoskeletal mesenchymal markers, adhesion proteins, and stem-cell-like proteins such as vimentin, neural cadherin (N-cadherin), cluster of differentiation-44 (CD44), and aldehyde dehydrogenase 1 (ALDH1). The gene discussed is EPCAM; the disease is neoplasm.