Silva et al. concluded that five-year overall and cancer-specific survival rates differed between patients with negative and positive Caspase 3 expression, agreeing with the observations of Tanimoto et al., who concluded that the five-year disease-specific survival rates of patients with and without Caspase 3 expression were 40.2% and 53.6%, respectively [14,70]. The gene discussed is CASP3; the disease is cancer.