According to the 2019 WHO classification, HCA is divided into four categories: HNF1α-inactivated HCA (H-HCA), inflammatory HCA (IHCA), beta-catenin-activated HCA (b-HCA), and β-catenin-activated IHCA (b-IHCA) [4,16]. The gene discussed is HNF1A; the disease is hepatocellular adenoma.