Peroxidasin (PXDN) is an extracellular matrix protein with peroxidase activity and has been reported to participate in epithelial mesenchymal transition processes, playing a promoting role in the proliferation, invasion, and migration of ovarian cancer cells through the regulation of PI3K (Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic) pathway activation Pl3k/Akt (AKT Serine/Threonine Kinase), and is considered a potential target for therapy [29]. This evidence concerns the gene MARK2 and ovarian cancer.