PADI4 inhibitor treatment in cancer cells downregulated four genes related to metastatic cancer phenotypes: Laminin Subunit Gamma 2 (LAMC2), C-X-C Motif Chemokine Ligand 8 (CXCL8), Niban Apoptosis Regulator 1 (FAM129A), and Pleckstrin 2 (PLEK2). Here, CXCL8 is linked to cancer.