MAPK8 and hepatocellular carcinoma: Wang et al. [51] showed that miR-302a inhibits cell proliferation and promotes the apoptosis of human HCC cells by targeting MAP3K2 and PBX3 to reduce the expression of the key MAPK-associated proteins, including phosphorylated ERK (p-ERK1/2), p38 (p-p38), and JNK (p-JNK).