The inhibitory effect of CSO on LPS-induced liver Il-1β and Il-6 expression is in accordance with data reported by Kang et al. [48] and Aboura et al. [49] showing that extracts of Ofi seeds or Ofi cladode infusion attenuated Il-1β and Il-6 expressions in high-fat diet-induced hepatic steatosis and inflammation, respectively. This evidence concerns the gene IL6 and craniosynostosis.