The aim of this study was to determine the role of TLR9 in immunopathogenesis of IgA nephropathy (IgAN) and membranoproliferative glomerulonephritis (MPGN) as potentially diagnostically useful molecules and to review their role in EBV incidence in patients with GN. Here, TLR9 is linked to membranoproliferative glomerulonephritis.