Syndromic diseases such as Lynch syndrome, Li–Fraumeni syndrome, Cowden syndrome/PTEN hamartoma tumor syndrome (PHTS), Peutz–Jeghers syndrome, DICER1 syndrome, and rhabdoid tumor predisposition syndrome—which are caused by GPVs in MMR genes, TP53, PTEN, STK11, DICER1, and SMARCB1/SMARCA4, respectively, and may also predispose to EOC [24,43,44]—can be characterized separately as syndromes. This evidence concerns the gene TP53 and PTEN hamartoma tumor syndrome.