Pancreatic cancer cell-derived hypoxic exosomes promote cell migration and tube formation of human umbilical vein endothelial cells (HUVECs) through the long noncoding RNA (lncRNA) UCA1, which acts as a sponge for miR-96-5p, impeding the inhibitory functions of miR-96-5p on the expression of its target gene AMOTL2 (angiomotin-like protein 2). Here, AMOTL2 is linked to pancreatic neoplasm.