S1PR2 and Hyperammonemia: Hyperammonemia increased the content of the GABA γ2 (Figure 8A–D), α2 (Figure 8E–H), and β3 (Figure 8I–L) subunits, which were completely reversed by blocking TrkB with ANA12, TNFR1 with R7050, S1PR2 with JTE-013, or CCR2 with RS504393 (Figure 8A–L).