The CDK8 rs17083838 minor allele (A allele) was significantly associated with overall sporadic pituitary adenomas under an additive (odds ratio (OR) 1.73, 95% confidence interval (CI) 1.19–2.50, p = 0.004) and dominant (OR 1.82, 95% CI 1.24–2.68, p = 0.002) inheritance model (Table 1). Here, CDK8 is linked to pituitary gland adenoma.