The most prospective predictive model to forecast the biochemical recurrence when looking at the primary tumor of locally advanced PCa was that based on changes in the expression of four mRNAs and one miRNA (ALDH3A2 + CHKA + ODF2 + QSOX2 + hsa-miR-503-5p, Figure 4, Table 3 and Table S4). The gene discussed is ALDH3A2; the disease is posterior cortical atrophy.