Concerning the eicosanoids (i.e., oxylipins derived from the 20-carbon PUFAs), the 5-LOX products of AA and EPA (i.e., 5-HETE and 5-HEPE) were lower, while 15-LOX products (15-HETrE and 15-HETE) were higher in MetS. Here, ALOX5 is linked to metabolic syndrome.