For the 5-LOX pathway, there were higher concentrations of two oxylipins in MetS participants, namely 5-HETE (+9.8%, p < 0.05) and 5-HEPE (+15.1%, p < 0.05) and the difference in 5-HETrE became significant (+35.3%, p < 0.001). The gene discussed is ALOX5; the disease is metabolic syndrome.