NLRP3 and Atrophy: They not merely found not only that the tail suspension group showed an obvious muscle atrophy compared with the heme chloride group and the expression of NLRP3, ASC and caspase-1 in the tibial anterior muscle was increased but also showed that the induction of heme oxygenase-1 could inhibit NLRP3 inflammasome activation and attenuate muscular atrophy.