As focal adhesion kinase (FAK) is involved in cell migration, adhesion, and apoptosis, and regulates PI3K/Akt cell signaling pathway [24,25], we assessed the influence of SH1, SH4, and SH11 on the expression of phosphorylated FAK (p-FAK) in MCF-7 breast cancer cells. The gene discussed is PTK2; the disease is breast cancer.