For example, colon cancer-associated transcript 1 (CCAT1), one well-studied eRNA transcribed from the 8q24 locus, can be activated through long-range interaction with MYC in many cancers, such as colorectal cancer (CRC), prostate adenocarcinoma (PRAD), breast invasive carcinoma (BRCA) and esophageal carcinoma (ESCA) [63,72,73,74]. Here, MYC is linked to cancer.