SPRY4 and glioblastoma: For instance, a pan-cancer analysis has displayed that the expression of eRNA SPRY4-AS1 in surgical specimens is associated with survivability in patients with HCC, glioblastoma multiforme (GBM), adrenocortical carcinoma (ACC), brain lower grade glioma (LGG) or mesothelioma (MESO) [103].