When a variant was identified in one of the MMR genes, the majority (58.56%, 65/111) corresponded to colorectal cancer, followed by endometrial cancer (18.02%, 20/111), ovarian cancer (10.81%, 12/111), breast cancer (4.50%, 5/111), and gastric cancer (1.80%, 2/111). The gene discussed is MRC1; the disease is breast carcinoma.