Below, we will discuss how these 12 proteins—MBP, PLK1, MECP2, MTMR7, TOX3, CPT1A, SORCS1, TRIM66, ITPR3, TTC28, CACNA1F, and PRAM1—and a number of additional molecules/proteins (most of which have also been linked to MS) operate in the framework. Here, PRAM1 is linked to myeloid sarcoma.