Nonetheless, our recently published cross-sectional study demonstrated increased Hsp90 plasma levels in IIM patients compared with healthy controls, which were associated with muscle involvement, higher disease activity, and several cytokines/chemokines (IL-1b, IL-6, IL-8, IL-17, interferon γ (IFN-γ), C-X-C motif chemokine ligand 10 (CXCL10), MCP-1, MIP-1α, MIP-1β, vascular endothelial growth factor (VEGF), and platelet-derived growth factor-(PDGF)-BB) previously implicated in the pathogenesis of IIM [20,21,22,33,34,35]. This evidence concerns the gene IFNG and acquired idiopathic inflammatory myopathy.