CD8A and systemic lupus erythematosus: Moreover, a recent analysis using K means clustering of mixed patients (pSS, SLE, and SLE/SS) revealed a group with divergent CD8+ T cell populations: decreased CD8+ CD127+CD25−, CD8+ CM, CD8+ naïve, and increased CD8+ TEMRA, CD8+CD25−CD127−, CD8+ T EM and total CD8+ T cells.