CD8A and glomerulosclerosis: Renal CD8+ T cell infiltration correlates with the renal activity index (r = 0.63, p = 0.0007) [136] high serum creatinine levels (r = 0.75, p = 0.0001) [136,137], SLEDAI (r = 0.14, p < 0.05) [137], proteinuria (r = 0.11, p < 0.05), glomerulosclerosis (r = 0.42, p < 0.001), and degree of tubulointerstitial inflammation (r = 0.46, p < 0.001) [137]. CD8+ T cell infiltrates associated with poor response to induction therapy [136] and ESRD progression (p < 0.001) [137].