The amplification of central/effector memory tumor-specific CTLs was observed for peripheral blood mononuclear cells (PBMCs) and tumor-infiltrating lymphocytes (TILs) samples from stage I–IV HLA-A*0201 melanoma patients stimulated with pDCs loaded with peptides derived from four melanoma TAAs (MelA, gp100, tyrosinase, and MAGE-A3). This evidence concerns the gene TYR and melanoma.