AFP and hepatocellular carcinoma: Fouda et al. analyzed the combination of AFP with miRNAs as a diagnostic biomarker for HCC, and discovered that the AUC value of the combination of AFP with miRNA-200, miRNA-29, miRNA-21, and miRNA-355 reached 0.92 [65], indicating that combination of miRNAs with AFPs potentially enhanced the diagnostic value of HCC.