The new findings in our study were that all of cytokines, including Th1 (IFN-γ), Th2 (IL-4, IL-13, Il-5, and IL-31), Th17 (IL-17), and Th22 (IL-22), were significantly decreased in AD-like skin lesions and plasma after application of CAPCS, and the levels were similar to those in the group treated with desonide. This evidence concerns the gene IL22 and Alzheimer disease.