The new findings in our study were that all of cytokines, including Th1 (IFN-γ), Th2 (IL-4, IL-13, Il-5, and IL-31), Th17 (IL-17), and Th22 (IL-22), were significantly decreased in AD-like skin lesions and plasma after application of CAPCS, and the levels were similar to those in the group treated with desonide. The gene discussed is IL31; the disease is Alzheimer disease.