More importantly, key genes of the respective pathways, such as AKT3, FGF2, FGF7, mitogen-activated protein kinase 4 (MAP3K4), MAP3K5, insulin receptor (INSR), AKT3, and mTOR, were also enriched in the analysis, thus explaining the link between diabetes and BCRL subjects in the present study. This evidence concerns the gene MAP3K4 and diabetes mellitus.