More importantly, key genes of the respective pathways, such as AKT3, FGF2, FGF7, mitogen-activated protein kinase 4 (MAP3K4), MAP3K5, insulin receptor (INSR), AKT3, and mTOR, were also enriched in the analysis, thus explaining the link between diabetes and BCRL subjects in the present study. The gene discussed is MAP3K5; the disease is diabetes mellitus.