Ginsenoside Rg3 attenuates Aβ-induced mitochondria-related apoptosis through the downregulation of Bax/caspase-9/caspase-3- and Bax/AIF-mediated apoptotic signaling in the hippocampus at 60 days after D-galactose-induced AD [57]. This evidence concerns the gene CASP9 and Alzheimer disease.