TNF and Sepsis: In this study, we investigated the effects of BGG on the LPS-stimulated murine macrophage cell line, RAW 264.7, on the production of pro-inflammatory mediators (NO and COX2) and cytokines (IL-6 and TNF, IFN) and also on an LPS-induced in vivo sepsis model as described by Haimei Tang et al. [25].