Thus, in radiation-induced lung fibrosis, increased expression of cytokines TNF-α, TGF-β1 and adhesion molecules ICAM-1 and VCAM-1 in lung epithelial cells and in damaged lung areas induces bone marrow MSCs migration through the circulatory system to the sites of lung damage and their differentiation into myofibroblasts [127]. Here, TGFB1 is linked to pulmonary fibrosis.